The drug is administered orally, as a rule, 1 time / day in the evening before bedtime, washed down with water or any drink. Adults and children over 12 years old - 1 tab. 1 time / day In the absence of effect, the dose can be increased to 2-3 tab. Children aged 6-12 years are prescribed 1/2 tab. 1 time / day and, if necessary, increase the dose to 1-2 tab. In the selection process, the same dose should be taken for several days and gradually increased by 1/2 tab. If, after reaching the maximum dose, there is no bowel movement within 3 days, a doctor should be consulted.

• Spastic constipation;
•  Intestinal obstruction;
•  Abdominal pain of unknown origin;
•  Atrangulated hernia;
•  Acute inflammatory diseases of the abdominal cavity; 
• Peritonitis; 
• Gastrointestinal and uterine bleeding;
• Cystitis; violations of water and electrolyte metabolism; 
• Hypersensitivity to drug components.

It is prescribed with caution for liver and / or kidney diseases, during pregnancy, during breastfeeding, in conditions after abdominal operations.

Application during pregnancy and lactation:

With caution, Senade® should be prescribed during pregnancy and during breastfeeding.

Application for violations of liver function: 

It is prescribed with caution for liver diseases. 

Application for impaired renal function: 

It is prescribed with caution for kidney disease.

Application in children: 

The drug is used in children aged 6 years and older.

From the digestive system: colicky abdominal pain, flatulence are possible; with prolonged use, especially in high doses, deposition of melanin in the intestinal mucosa, nausea, vomiting, diarrhea are possible. From the side of metabolism: with prolonged use, especially in high doses, violations of water-electrolyte metabolism, deposition of melanin in the intestinal mucosa are possible. From the urinary system: with prolonged use, especially in high doses, albuminuria, hematuria, discoloration of urine are possible. From the side of the central nervous system: with prolonged use, especially in high doses, convulsions, fatigue, confusion are possible. Dermatological reactions: with prolonged use, especially in high doses, skin rash is possible. From the side of the cardiovascular system: with prolonged use, especially in high doses, vascular collapse is possible.

Long-term use of Senade® in high doses may increase the action of cardiac glycosides and influence the action of antiarrhythmic drugs due to the possibility of hypokalemia. With simultaneous use with thiazide diuretics, corticosteroids, licorice root preparations, the risk of hypokalemia increases.

Symptoms: Diarrhea leading to dehydration. Treatment: Increasing fluid intake is usually sufficient to compensate for fluid and electrolyte loss. In some cases, it is required to replace the loss of fluid and electrolytes with the help of intravenous infusion of plasma substitutes.