The drug is administered orally.

For acute diarrhea in adults and elderly patients: the initial dose is 4 mg, then 2 mg after each act of defecation in the case of loose stools. Children over 6 years of age: the initial dose is 2 mg, then 2 mg after each act of defecation in the case of loose stools.

In chronic diarrhea, adults and elderly patients are prescribed an initial dose of 4 mg / day. Further, the dose is adjusted so that the stool frequency is 1-2 times / day, which is usually achieved with a maintenance dose of 2-12 mg / day. Children over 6 years of age are prescribed an initial dose of 2 mg / day. Further, the dose is adjusted so that the stool frequency is 1-2 times / day, which is usually achieved with a maintenance dose of 2-12 mg / day.

The maximum daily dose for acute and chronic diarrhea in adults is 16 mg; in children - 6 mg per 20 kg of body weight - up to 16 mg.

When normal stool appears or in the absence of stool for more than 12 hours, the drug is canceled.

The lozenge should be placed on the tongue. Within a few seconds, it dissolves on the surface of the tongue and can be swallowed with saliva without drinking water.

Children's age (up to 6 years old); hypersensitivity to loperamide and / or other components of the drug; acute dysentery and other infections of the gastrointestinal tract (caused by, including Salmonella, Shigella and Campylobacter); intestinal obstruction (including, if necessary, avoiding suppression of peristalsis), diverticulosis, acute ulcerative colitis or pseudomembranous enterocolitis (diarrhea (diarrhea) caused by taking antibiotics); first trimester of pregnancy; lactation period.

Allergic reactions (skin rash); constipation and / or bloating; intestinal colic; retention of urine (rare); intestinal obstruction (very rare); pain or discomfort in the abdomen; nausea, vomiting; fatigue; drowsiness, dizziness; dry mouth; a burning or tingling sensation of the tongue that occurs immediately after taking the lozenges.

There is no information.

Symptoms: depression of the central nervous system (CNS): stupor, impaired coordination, drowsiness, miosis, increased muscle tone, respiratory depression; intestinal obstruction. Children are more sensitive to the effects on the central nervous system. Treatment. Symptomatic treatment: gastric lavage, activated charcoal (no later than 3 hours after taking the drug), artificial ventilation. The antidote is naloxone. Since the duration of action of the drug is longer than that of naloxone (1-3 hours), re-administration of the latter may be required. To detect possible depression of the central nervous system, the patient should be closely monitored for at least 48 hours.