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Buy Bromhexine Syrup-Acute 4 mg / 5 ml syrup: 100 ml bottle online. Free worldwide shipping. 

Brand: GRINDEX, AO 

Drug form: Syrup

Manufacturers: Latvia

Active substance: Bromhexine hydrochloride

Group: Mucolytic agent

Expiration date: 5years

 

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BROMHEXINE Syrup-Acute 4mg/5ml syrup: 100 ml bottle

SKU: 164
$19.00Price
  • Indications for use of Bromhexine are:

    Diseases of the respiratory tract, accompanied by the formation of hard-to-separate viscous secretions: tracheobronchitis, chronic bronchitis with a broncho-obstructive component, bronchial asthma, cystic fibrosis, chronic pneumonia.

    Pharmachologic effect:

    Mucolytic agent with expectorant action. Reduces the viscosity of bronchial secretions due to depolarization of the acidic polysaccharides contained in it and stimulation of the secretory cells of the bronchial mucosa, which produce a secret containing neutral polysaccharides. It is believed that bromhexine promotes the formation of a surfactant.

    Pharmacokinetics:

    Bromhexine is rapidly absorbed from the gastrointestinal tract and undergoes intensive metabolism during the "first pass" through the liver. Bioavailability is about 20%. In healthy patients, Cmax in plasma is determined after 1 hour.

    It is widely distributed in body tissues. About 85-90% is excreted in the urine mainly in the form of metabolites. The metabolite of bromhexine is ambroxol.

    Plasma protein binding of bromhexine is high. T1 / 2 in the terminal phase is about 12 hours.

    Bromhexine penetrates the BBB. In small quantities, it crosses the placental barrier.

    Only small amounts are excreted in the urine with a T1 / 2 6.5 h.

    The clearance of bromhexine or its metabolites may decrease in patients with severe hepatic and renal impairment.

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